中文版   ENGLISH
产品搜索
产品类别
 OLED、OPV材料
 天然香料
 医药中间体
联系lols9竞猜
lols9竞猜-官网
地址:苏州工业园区长阳街415号
电话:0512-62867016
传真:0512-62867017
订购/客服:sale@gr-chem.com
QQ:
技术咨询:tech@gr-chem.com
QQ:
 
产品展示
产品编号:gr-c001
产品CAS号:405060-95-9
英文名:(E)-3-phenyl-N-[2,2,2-trichloro-1-(quinolin-8-ylcarbamothioylamino)ethyl]prop-2-enamide
中文名:Salubrinal抑制剂
分子式:C21H17Cl3N4OS
分子量:479.81
 

产品详情简介

Salubrinal is a cell-permeable and selective inhibitor of the phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF-2α). Shown to protect cells from endoplasmic reticulum (ER) stress-induced apoptosis (EC50~15μM) in PC12 cell lines induced with the protein glycosylation inhibitor tunicamycin (sc-201539), and brefeldin A (sc-200861), which causes ER stress by blocking ER-to-Golgi vesicle transport. Salubrinal is a potentially useful agent to study mechanisms of ER stress-induced apoptosis.

发送询盘   * 必填项
公司名称:
电子邮箱:*
联系人:*
手机号码:
需求描述:*